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Symptomatology as you describe is not to be ignored--its a warning sign that something may be wrong inside your abdomen. Over-the-counter therapiessuch as ginger, vitamin B-6 supplements, and doxylamine (Unisom)can also help soothe your symptoms. According to the American Psychological Association (APA), stress affects all systems in the body and can have severe effects if it becomes long-term or chronic. According to John Hopkins Medicine, constipation is the most common digestive condition in the United States. While most headaches and loss of appetite subside with time, others can signal a medical emergency. Other symptoms typically include: vomiting diarrhea fever a headache body aches Most of the time, GI. Scientists use genetic rewiring to increase lifespan of cells. This information is not intended as a substitute for professional medical care. However, there are several conditions that can cause headaches, nausea, and fatigue that may require medical attention. Migraine & Headaches Center: Physician Reviewed Headache - WebMD People may be able to improve the quality of their sleep by: Dehydration can lead to decreased energy levels and feelings of fatigue. Some other signs of fatigue include feeling: Loss of appetite means you dont have the same desire to eat as you used to. Fatigue is a nonspecific symptom that can occur with most illnesses. end-stage kidney disease. Prolonged loss of appetite can affect your overall health. Headache and nausea: Severe headache with fatigue and nausea are possible symptoms of migraine headache, which can last up to 72 hours and classically occur on one side of. Norovirus infections account for 1 in 5 cases of viral gastroenteritis worldwide. Age 45.period two weeks early. Your doctor will try to identify and treat any underlying causes. (2016). Then call 999 for an ambulance, saying it's an "adrenal crisis" or "Addisonian crisis".